IVF What is the treatment?
History of IVF Treatment
IVF (In Vitro Fertilization) treatment is one of the most important assisted reproductive technologies developed for couples who cannot have children naturally. Its development process is considered one of the most striking achievements of modern medicine.
a. First Developments
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1944John Rock and Miriam Menkin fertilized a human egg in a laboratory for the first time, but embryo development was not achieved.
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1978: The first successful IVF birth in the world took place. In England, with the method developed by Dr. Robert Edwards and Dr. Patrick Steptoe Louise Brown A baby girl named was born. This is considered a milestone in medicine.
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2010: Dr. Robert Edwards was awarded the Nobel Prize in Medicine for his contributions to the development of IVF technique.
b. IVF in Türkiye
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1989: The first IVF was successfully born in Türkiye. This development led to the rapid spread of assisted reproductive techniques in the country.
IVF To whom and how Is it applied?
What is the Rosi Technique?
It is a fertilization method in which sperm cells are selected with a microscope and sperm-egg adhesion is achieved using electricity.
In Vitro Fertilization PRP Method
As women get older, ovulation disorders and abnormal diseases can cause infertility.
Electrofusion Technique
In order for the sperm to activate or fertilize the egg, it must contain certain substances and fluids.
Drug-Free IVF
We have been successfully continuing the IVM, that is, drug-free IVF technique, for many years. IVM treatment should be done carefully and appropriately.
Embryo Detox
This method, called egg maturation culture fluid and cell therapy, or simply embryo detox, improves the chances of becoming a mother.
Fallow Technique
The uterine factor is very important in in vitro fertilization treatment. In order for the embryo to hold on healthily, the uterus must
Micro Chip Method
Although the microchip method is mostly preferred in treatments caused by male infertility, it can be used in infertility caused by other reasons.
Assisted hatching
“Assisted Hatching” is an auxiliary method used during IVF treatment.
ICSI & Microinjection
Microinjection method is used in cases of male infertility where sperm motility is low and morphology is distorted.
PBMC Infusion
Uterine immunity treatment with Fertility Vaccine is carried out in two stages... The application is carried out in two stages.
IUI Technique
To give a short answer to insemination, it means that all the sperm taken from the man is transferred into the woman's uterus.
Exosome Therapy
Exosomes are small vesicles released by cells that enable intercellular communication.
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Who is IVF Treatment Applied to?
In vitro fertilization treatment can be applied to people with unexplained infertility, which can also be referred to as infertility. Additionally, IVF treatment may be required in the following cases:
- In case both fallopian tubes are blocked in women.
- Ovulation disorders and advanced polycystic ovary syndrome.
- Low ovarian reserve.
- Endometriosis disease and chocolate cyst (endometrioma).
- Advanced age (in women).
- Disorders in sperm count and quality, azoospermia conditions.
- Failure of vaccination practices.
- Immunological problems.
- Finding conditions that require genetic investigation.
IVF Stages
In Vitro Fertilization Examination, Treatment Plan and First Interview
The first stage of in vitro fertilization treatment is the first meeting with people considering treatment. At this stage, it is investigated whether treatment is needed and a treatment plan is created if needed.
Egg Collection
After the first meeting, the ovarian stimulation phase begins. On the second or third day of the menstrual period, the uterus and ovaries are checked with ultrasound. If there is no problem, hormone therapy is started for egg development. When the eggs reach a certain size, a cracking injection is made and then the egg collection is performed.
Egg collection is performed under anesthesia and takes approximately 20-30 minutes.
Embryology, Laboratory Process
After the eggs are collected, the fertilization process is carried out in a laboratory environment. The sperm fertilization process is applied to the selected eggs. The development of fertilized eggs is monitored and quality embryos are selected and placed in the uterus. The transfer process is usually performed on the third or fifth day.
Embryo Transfer
Embryo transfer is a painless procedure and does not require anesthesia. After the uterine area is cleaned, the embryos are carefully placed into the uterus. After the transfer process, a period of time is waited for the embryos to settle and develop in the uterus, and then a pregnancy test is performed 12 days later.
What is the In Vitro Fertilization Treatment Duration?
In vitro fertilization treatment begins on the second or third day of the menstrual period and lasts approximately 15-18 days. Treatment duration may vary depending on the drug dose used and the characteristics of the patients.
What is the In Vitro Fertilization Success Rate and How Can It Be Increased?
The success rate of in vitro fertilization treatment varies depending on the center applying the treatment and the characteristics of the couple. Generally, the success rate varies between 30% and 70%. The woman's age is the most important factor affecting treatment. Advancing age may reduce the success rate. Also, sperm status is important. Special treatment methods can increase the chances of success.
The main factor affecting the success rate in infertility treatment is the woman's age. The ideal reproductive period for women is between the ages of 20 and 30. For this reason, the success rate decreases with advancing age compared to younger women. For this reason, although the success rate decreases in older women, the condition of the sperm also affects the chance of treatment. One of the Special Treatment Methods Balancing Technique or In Vitro Fertilization PRP Method The chance of success can be increased with .
Preparation for IVF Treatment
Before starting in vitro fertilization treatment, tests such as ovarian reserve test and semen analysis are performed. Infection screenings and intrauterine evaluations are also performed. Necessary precautions are taken and preparations are made for treatment.
Methods Used in IVF Treatment
One of the most commonly used methods in in vitro fertilization treatment is microinjection. Microinjection is applied in cases where sperm count and quality are low. In Vitro Maturation is used in patients with high egg reserve.
What is the Price of IVF?
The price of in vitro fertilization treatment varies depending on many factors. These factors include the patients' condition, their age, the complexity of the treatment process, additional procedures, and the center's policies. Prices may vary depending on the centre.
The Most Affordable IVF Price
Factors that affect the price include the complexity of the treatment process, additional procedures and pre-treatment tests. You can get an affordable treatment by creating a good treatment plan and choosing a suitable IVF center.
egg collection, embryo Creation and transfer to the mother's uterus constitute the IVF treatment process. Procedures such as analysis, test, and uterine film may be requested before starting the treatment process. IVF price THESISIn addition to procedures such as Micro Tese, ICSI, Rosi, embryo freezing, genetic examination and similar activities before treatment may be among the determining factors in IVF prices.