Gynecology and Obstetrics Specialist Prof. said that the data obtained in their study on male infertility was satisfactory. Dr. Timur Gürgan, He noted that the main problems that occur in male sperm are maturation and genetic problems.

Stating that they have done various tests regarding infertility, Gürgan said, “The most important problem that we have not been able to solve so far is that sperm production in the testicles has decreased and immature sperm are evident. In fact, with some surgeries, we were dealing with cases where we could not find any sperm or fertilize the egg. There are studies we have done in recent years. Our work, especially with the Japanese group, has been going on for 2 years. "The data we obtained in these studies are encouraging," he said.

“This broke new ground”

Noting that they found immature and round sperm in the samples obtained from the men's testicles. Prof. Dr. Timur Gürgan He said:

What is Rosi?

“We were able to achieve fertilization by ensuring that these sperm adhere to the egg using the electrofusion technique. This broke new ground. We call this technique Round Spermatid Injection (Rosi). It is now a fact that with this technique, the sperm fertilizes the egg, development progresses well, and pregnancy occurs when the fertilized eggs are introduced into the woman's uterus. "The Rosi method has become a new ray of hope in cases that were very hopeless until now and where no positive results were obtained despite the presence of undeveloped round sperm."

Stating that studies on the subject are continuing, Gürgan emphasized that there are patients who achieved pregnancy using this technique.

What is the Rosi method and who can benefit from it?

Gürgan said, “I would like to touch on one issue in particular. This is not a magic technique. It needs to be done very carefully. Experienced, in good places, without running into profit. When it is performed on special and appropriate patients, it provides a ray of hope to couples who do not have the chance to have children. We are a center that has achieved this in Turkey. "At the end of 2 years, we achieved our first pregnancy," he said.

Gynecology and Obstetrics Specialist Prof.Dr. Timur Gürgan added that pregnancy rates with the Rosi technique are seen to be in the range of 20 percent, and that it is an important step for medicine for couples with zero chance to reach this rate.

What is the Rosi Technique? “Round Spermatid Injection”

“Round Spermatid Injection (ROSI)” is a reproductive technology method in which the immature precursors of male reproductive cells, namely round spermatids, are injected into the ovarian cell for fertilization. This method may be an option for couples who cannot have children naturally due to sperm production disorders in men.

Normally, in men, spermatids go through a series of maturation steps to develop into mature sperm cells. However, in some cases, this maturation process may be incomplete and round spermatids may form. The ROSI method involves taking these round spermatids and injecting them into the egg cell using specialized injection techniques in a laboratory environment.

The ROSI method is generally applied during the in vitro fertilization (IVF) process. During this process, the woman's eggs are collected and fertilization is carried out in the laboratory. Unlike the normal IVF method, the ROSI method provides fertilization by using immature spermatids. Therefore, ROSI may offer a solution for men with lack of maturation of spermatids or other sperm production problems.

Those who got pregnant with the Rosi Technique:
A Promising Journey

While reproductive health represents one of the most precious moments of their lives for many couples, for some it can be a journey full of unexpected challenges. Gürgan Clinic In Vitro Fertilization Center stands out as a center that draws attention with its innovations in reproductive health and achieves promising results using the "Round Spermatid Injection (Rosi)" method. Rosi offers a way out for couples with sperm maturation problems and is seen as an important step in increasing the chances of becoming a father.

The Rosi technique may be a ray of hope for couples who have a low chance of getting pregnant naturally due to problems in the sperm maturation process in men. This method, which is performed especially by using round spermatids, involves transferring immature sperm cells to the egg cell using special injection techniques in a laboratory environment.

Gürgan Clinic IVF Center offers examples of success among couples using the Rosi method. Cases where this technology has been used include many couples who have left hopelessness behind and achieved their dream of starting a family. Rosi's success rates can change the lives of couples by providing a huge increase, especially in cases where the chance of becoming a father is almost zero. Studies conducted at Gürgan Clinic In Vitro Fertilization Center show that the chance of becoming a father increases by a significant 13% with the Rosi method.

These achievements show the latest point in research and technology in the field of IVF. The Rosi method offers couples a new beginning, leaving hopelessness and uncertainty behind. Gürgan Clinic In Vitro Fertilization Center supports couples to maximize Rosi's chance of success with its experienced expert staff and the latest technologies.

As a result, the Rosi method is not only a step forward in reproductive technologies, but also an opportunity to revive hope. Gürgan Clinic IVF Center contains the stories of many couples who became pregnant with Rosi, and thanks to this technology, families have the chance to come together again.

How and to whom is the Rosi Method performed?

The Rosi method can be used as an option for couples who have a low chance of conceiving a child naturally due to reproductive health problems. This method usually targets conditions caused by problems in sperm production in men.

The ROSI method involves injecting immature spermatids (round spermatids) into the egg cell using special injection techniques in a laboratory environment. In this way, it is aimed for spermatids that have not completed the maturation process to gain the ability to fertilize.

The Rosi method can generally be considered for the following situations:

1. Sperm Maturation Problems: Normal sperm production may not occur in men due to sperm maturation problems. The Rosi method may be an option for couples with such problems as it involves the use of immature spermatids.
2. Obstructive Azoospermia: In some men, sperm may not be able to come out during ejaculation due to blockage in the sperm ducts. The Rosi method can increase the likelihood of fertilization in men with this condition by using spermatids.
3. Genetic Problems: Normal sperm cells may not be produced due to genetic problems in sperm production. The Rosi method may offer an option to couples who experience sperm production problems due to such genetic problems.
4. Couples with Low Possibility of Becoming a Father: For men who are unlikely to become fathers, the ROSI method can be considered as an option to increase the chances of becoming pregnant.

Can the Rosi technique be performed on patients with genetic problems?

Genetic problems such as Klinefelter syndrome can be a major obstacle for couples experiencing serious reproductive health challenges. However, advanced reproductive technologies such as the Rosi (Round Spermatid Injection) method may offer a promising solution for such situations. Gürgan Clinical In Vitro Fertilization Center achieves positive results by using the Rosi technique to raise the hopes of patients with Klinefelter syndrome.

Klinefelter syndrome is a genetic disease that is not considered rare considering its prevalence. In this syndrome, patients' testicles may be smaller than normal and their reproductive abilities may be affected. Therefore, using specialized methods such as ROSI therapy may be an important step. Gürgan Clinical In Vitro Fertilization Center increases the chances of success by carefully planning the treatment processes of patients with Klinefelter syndrome.

Before treatment with Rosi, patients' general health conditions are evaluated and testosterone levels are checked. Having normal testosterone levels is important for the effectiveness of the treatment process. Hormone levels and testicular examination findings are meticulously evaluated by experienced urologists of Gürgan Clinical In Vitro Fertilization Center. Suitable patients are selected for IVF treatment with the Rosi technique.

The examinations made before the treatment with Rosi are similar to the evaluations made before the microTESE procedure. Treatment processes for patients with Klinefelter syndrome are adapted to individual needs and health conditions. Gürgan Clinical In Vitro Fertilization Center helps revive couples' hopes by providing both medical and emotional support regarding the Rosi Technique treatment.

In short, genetic problems such as Klinefelter syndrome can be overcome with Rosi treatment. The experienced team of Gürgan Clinical In Vitro Fertilization Center carefully evaluates the patients' conditions, determines the most appropriate treatment path and offers couples a hopeful journey.

Rosi Technique Success Rate:
A Treatment Way That Raises Hope

While the Rosi technique is evaluated for hopeful patients, the success rates of the treatment are also an important issue. The chances of success of this method are of great interest to couples considering treatment. Although the data we currently have comes mostly from Japan, good results have begun to be obtained in our country as well. It is stated that the success rate of this treatment is on average over 10%.

As Gürgan IVF Center, we have a positive impact on the data in our country by successfully applying the Rosi method. There is strong data that the chance of success can increase with our increasing experience and revision of the method every year.

Round Spermatid Injection “Rosi” technique is considered as a treatment alternative, especially in azoospermic infertile patients who have previously undergone Micro Tese procedure and have not been able to obtain sperm cells.

Although the Rosi technique is a treatment that should be considered first in male infertility, it is not a method that can be applied to every patient. The treatment decision is made by a urologist based on genetic, hormonal and examination results. Spouses of patients deemed suitable for this treatment are examined in detail by gynecologists.

This treatment is a process that requires cooperation of couples. Rosi treatment involves combining the egg and sperm cell using microinjection method. The embryo formed after this stage is transferred to the woman after an appropriate period of time. Rosi pregnancies are followed like normal pregnancies, but are examined more closely and managed with care.

As Gürgan IVF Center, we support the hopes of couples with our expert team and experience in the Rosi method. Before starting the treatment, all details and processes are explained to the couples in detail and we make them feel that we are with them at every step.