What is Microinjection & ICSI?
Microinjection method increases the chance of pregnancy in cases of male infertility where sperm motility is low, morphology is distorted or their number is low.
Microinjection & ICSI
Microinjection method in male infertility It is widely used. In cases where sperm motility is low, morphology is distorted or their number is low micro injection or alias ICSI It increases the chance of pregnancy. Nowadays, many IVF centers use the microinjection (ICSI) method. This is because Intracytoplasmic Sperm Injection (ICSI)The success rate of the method, also called , is higher. In this method, fertilization is done in a laboratory environment, not in the uterus. Classic IVF methodThe biggest difference from the classical method is that in the classical method, a large number of sperm are deposited around the egg taken from the uterus in a laboratory environment and waited for fertilization. In the microinjection method, the sperm taken from the expectant father is injected into the egg taken from the expectant mother.
When sperm motility is low
Hope of becoming a father:
ICSI & Microinjection Method
“ICSI” (Intracytoplasmic Sperm Injection) is an IVF method also known as microinjection. ICSI is a fertilization method in which the sperm cell is injected directly into the egg cell. This method is used in men with low sperm motility or count or when other fertilization methods have failed.
The ICSI process usually includes these steps:
- Collecting Eggs: The procedure is performed in which mature eggs are collected from the woman's ovaries.
- Preparation of Sperm Sample: The sperm sample taken from the man is subjected to a special process in a laboratory environment. This process ensures the selection and preparation of sperm of the best quality.
- Microinjection: The prepared egg and selected sperm cell are carefully evaluated under a microscope. Using a microsyringe, a sperm cell is injected into the egg cell by puncturing its membrane.
- Waiting for Fertilization: The sperm injected into the egg cell naturally mimics the fertilization process and fertilization is expected.
- Embryo Development: The fertilized egg begins to develop into a cluster of cells called an embryo. These embryos are developed under laboratory conditions over several days.
- Embryo Transfer: The best quality and appropriate number of embryos are transferred to the woman's uterus. This transfer process is usually performed for day 3 or 5 embryos.
The ICSI method is used as a solution for couples with sperm cell problems or men experiencing sperm production problems. It is an effective option especially for conditions such as azoospermia (lack of sperm), oligospermia (low sperm count) or asthenospermia (low sperm motility). Thanks to this method, the fertilization process is controlled more closely and successful results can be achieved.
How long has the microinjection method been used?
The microinjection method was first used in Belgium in 1992. With this method, couples who failed to have a baby with the old methods got the chance to have a baby. Azoospermia This method, which increases the chances of pregnant men to become fathers, has been applied in our country for many years.
Advantages of Micro injection Method
Microinjection method in general sperm It provides a great advantage in cases where sperm count is low, sperm motility is slow and sperm morphology is distorted. Dropping sperm directly into the egg is an important factor in ensuring a higher fertilization rate and achieving success. In the ICSI method, the amount of sperm is not related to the fertilization rate. Male factor infertilityICSI can also be performed by obtaining one or two sperm via TESE, TESA or Micro TESE methods.
To whom is ICSI applied?
Couples who have had fertilization problems in their previous treatments, couples who have sperm count-shape-motility problems, TESE – TESA – Micro TESE Surgical Procedures In cases where sperm is required to be obtained via microinjection (ICSI) method is applied.
Does the Risk of Anomaly Increase in the Micro Injection Method?
It is still debated whether the risk of structural or physical anomalies in newborn babies increases with the microinjection method. In line with the research conducted, microinjection or ivf No different findings were observed in babies born with treatment than in naturally occurring pregnancies. It seems useful to perform chromosome analysis in men who are at risk of anomaly in their genetic structure. Additionally, genetic screening will reduce the risk of anomalies.
